Background: Magnetic resonance imaging of breast, reported to be a high sensitivity of 94% to 100%, is themost sensitive method for detection of breast cancer. The purpose of this study was to investigate our clinicalexperience in MRI-guided breast lesion wire localization in Chinese women. Materials and
Methods: A total of44 patients with 46 lesions undergoing MRI-guided breast lesion localization were prospectively entered intothis study between November 2013 and September 2014. Samples were collected using a 1.5-T magnet with aspecial MR biopsy positioning frame device. We evaluated clinical lesion characteristics on pre-biopsy MRI,pathologic results, and dynamic curve type baseline analysis.
Results: Of the total of 46 wire localization excisionbiopsied lesions carried out in 44 female patients, pathology revealed fourteen malignancies (14/46, 30.4%) andthirty-two benign lesions (32/46, 69.6%). All lesions were successfully localized followed by excision biopsy andassessed for morphologic features highly suggestive of malignancy according to the American College of RadiologyBreast Imaging Reporting and Data System (BI-RADS) category of MRI (C4a=18, C4b=17, C4c=8,C5=3). Of46 lesions, 37 were masses and 9 were non-mass enhancement lesions. Thirty-two lesions showed a continuouskinetics curve, 11 were plateau and 3 were washout.
Conclusions: Our study showed success in MRI-guidedbreast lesion wire localization with a satisfactory cancer diagnosis rate of 30.4%. MRI-guided wire localizationbreast lesion open biopsy is a safe and effective tool for the workup of suspicious lesions seen on breast MRIalone without major complications. This may contribute to increasing the diagnosis rate of early breast cancerand improve the prognosis in Chinese women.