Background: The Functional Assessment of Cancer Therapy - Breast (FACT-B) scale is widely used tomeasure health-related quality of life in cancer patients. The aim of the present study is to validate the FACT-Bin a sample of Iranian women with breast cancer. Materials and
Methods: The sample consisted of 300 womenselected through non-random convenient sampling procedure from oncology hospitals and clinics in Kermanshahand Shiraz cities. They were asked to fill in the Persian versions of the FACT-B scale, Hospital Anxiety andDepression Scale, the European Organization for Research and Treatment of Cancer quality of life EORTCQLQ30. Confirmatory factorial analysis of the methods, concurrent validity and discriminant, and Cronbach’salpha for internal consistency were applied.
Results: Internal consistency using Cronbach’s alpha was 0.63 to0.93 for the subscales and 0.92 for the total scale. Significant correlations between FACT- B and other measuresindicate that this scale had concurrent and discriminant validity. The values of fit indices were satisfactory.
Conclusions: The Persian version of the FACT-B scale is valid and reliable and, therefore, the scale can be usedin research and clinical settings to assess health-related quality of life in Iranian patients with breast cancer.