Salivary Levels of ErbB2 and CEA in Oral Squamous Cell Carcinoma Patients


Oral and Dental Disease Research Center, Department of Oral Medicine, School of Dentistry, Zahedan, Iran E-mail:


Oral squamous cell carcinoma (OSCC) is one of the ten most common causes of cancer death worldwide. Assessment of molecular changes can help detect and control lesions. The aim of this study was evaluation of salivary levels of ErbB2 and CEA in OSCC patients. In this case-control study, 27 OSCC patients and 26 healthy controls participated. After obtaining consent and filling out a questionnaire, unstimulated saliva samples were collected from people in the morning for measurement of the two markers using ELISA. Data were analyzed using Mann Whitney U test in SPSS 19 software with P