Pramual, P., Sarakarn, P., Kamsa-ard, S., Jirapornkul, C., Maneenin, N., Thavondunstid, P., Juntarach, P., Promthet, S. (2018). Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial. Asian Pacific Journal of Cancer Prevention, 19(1), 271-278. doi: 10.22034/APJCP.2018.19.1.271
Putthikrai Pramual; Pongdech Sarakarn; Siriporn Kamsa-ard; Chananya Jirapornkul; Naowarat Maneenin; Prasert Thavondunstid; Prachak Juntarach; Supannee Promthet. "Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial". Asian Pacific Journal of Cancer Prevention, 19, 1, 2018, 271-278. doi: 10.22034/APJCP.2018.19.1.271
Pramual, P., Sarakarn, P., Kamsa-ard, S., Jirapornkul, C., Maneenin, N., Thavondunstid, P., Juntarach, P., Promthet, S. (2018). 'Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial', Asian Pacific Journal of Cancer Prevention, 19(1), pp. 271-278. doi: 10.22034/APJCP.2018.19.1.271
Pramual, P., Sarakarn, P., Kamsa-ard, S., Jirapornkul, C., Maneenin, N., Thavondunstid, P., Juntarach, P., Promthet, S. Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial. Asian Pacific Journal of Cancer Prevention, 2018; 19(1): 271-278. doi: 10.22034/APJCP.2018.19.1.271
Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial
1Doctor of Public Health Program, Faculty of Public Health, Khon Kaen University, Thailand.
2ASEAN Cancer Epidemiology and Prevention Research Group, Khon Kaen University, Thailand.
3Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Thailand.
4Department of Public Health Administration, Health Promotion and Nutrition, Faculty of Public Health, Khon Kaen University, Thailand.
5Namphong District Public health Office, Khon Kaen University, Thailand.
Receive Date: 07 November 2017,
Revise Date: 06 December 2017,
Accept Date: 16 December 2017
Abstract
Background: There is convincing evidence from epidemiological studies that meat consumption increases colorectal cancer (CRC) risk. However, assessment of any association with a positive fecal immunochemical test (FIT) in CRC screening has been limited. If a link could be shown this might be helpful for establishing a risk group for colonoscopy. Objective: This study aimed to assess any association between meat consumption and other lifestyle factors and a positive FIT result in a Thai population. Methods: A cross-sectional analytical study was conducted with 1,167 participants in a population-based randomized controlled trial. CRC was screened from May 2016 - February 2017. Subjects aged 45-74 years who met the eligibility criteria were randomly allocated to the study arm. A positive FIT was determined with cut-off 100 ng/mL. Multiple logistic regression was used to analyze any relationship between lifestyle factors and a positive FIT. Result: The total number of subjects was 1,060 (90.8% return rate of FIT). With FIT100, FIT150, and FIT200, positive tests were found in 92 (8.68%), 74 (6.98%), and 60 (5.66%), respectively. No significant associations were noted with any of the variables, except for being aged 60-74 years (ORadj = 1.62, 95% CI: 1.03-2.54) Borderline significance was observed for high consumption of vegetables (ORadj = 0.62, 95% CI: 0.36-1.07) and being male (ORadj = 1.39, 95% CI: 0.87-2.22). Conclusion: Despite the evidence from the literature, no association was here found between a positive FIT result and meat consumption or other well-established lifestyle parameters. Being aged 60-74 years was a risk factor which should be taken into account in CRC screening strategy in countries like Thailand with limited access to endoscopy.
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