Document Type: Research Articles
Faculdade de Medicina da UFMG. Belo Horizonte, Minas Gerais, Brazil.
Divisão de Ensaios Clínicos e Desenvolvimento de Fármacos, Instituto Nacional de Câncer (INCA). Rio de Janeiro, Rio de Janeiro, Brazil.
Departamento de pesquisa clínica do Instituto Nacional de Câncer (INCA), Rio de Janeiro, Rio de Janeiro, Brazil.
Faculdade de Medicina da Universidade de Itaúna. Itaúna, Minas Gerais, Brazil.
Objective: To analyze differences in survival between black and non-black women diagnosed with cervical cancer
and treated at the National Cancer Institute in Brazil. Methods: This retrospective cohort study was conducted using
medical records of patients who were treated for cervical cancer between 2006 and 2009 at the Brazilian National Cancer
Institute - Rio de Janeiro - Brazil. The clinical and epidemiological characteristics of black and non-black patients were
compared using the chi-square test. Survival functions over five years were calculated using the Kaplan-Meier estimator
and compared using the log-rank test. Associations between race and mortality risk were analyzed using the Cox
proportional hazards model. P-values women, of whom 188 (12.7%) were black, 1,209 (81.6%) were non-black and 85 (5.7%) were of unspecified race.
The age at diagnosis of the patients ranged from 19 to 84 years (mean 50.1 years; SD±13.2). Hemoglobin at the time of diagnosis (p=0.008) and absence of surgery as primary treatment (p = 0.005) were more frequent
among black women. Cox analysis adjusted for these two factors showed no statistically significant difference in the
mortality risk associated with cervical cancer among black and non-black women (HR=1.1 95% CI 0.9-1.5; p=0.27).
Conclusion: After adjusting for hemoglobin levels and surgery, race alone was not shown to be a prognostic factor
for patients with cervical cancer.