Nosratzehi, T., Raiesi, M., Shahryari, B. (2018). Lack of Association between Oral Lichen Planus and Hepatitis B and C Virus Infection - a Report from Southeast Iran. Asian Pacific Journal of Cancer Prevention, 19(6), 1633-1637. doi: 10.22034/APJCP.2018.19.6.1633
Tahereh Nosratzehi; Mehrab Raiesi; Bahareh Shahryari. "Lack of Association between Oral Lichen Planus and Hepatitis B and C Virus Infection - a Report from Southeast Iran". Asian Pacific Journal of Cancer Prevention, 19, 6, 2018, 1633-1637. doi: 10.22034/APJCP.2018.19.6.1633
Nosratzehi, T., Raiesi, M., Shahryari, B. (2018). 'Lack of Association between Oral Lichen Planus and Hepatitis B and C Virus Infection - a Report from Southeast Iran', Asian Pacific Journal of Cancer Prevention, 19(6), pp. 1633-1637. doi: 10.22034/APJCP.2018.19.6.1633
Nosratzehi, T., Raiesi, M., Shahryari, B. Lack of Association between Oral Lichen Planus and Hepatitis B and C Virus Infection - a Report from Southeast Iran. Asian Pacific Journal of Cancer Prevention, 2018; 19(6): 1633-1637. doi: 10.22034/APJCP.2018.19.6.1633
Lack of Association between Oral Lichen Planus and Hepatitis B and C Virus Infection - a Report from Southeast Iran
1Dental Research Center, Faculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
2General Dentist, Zahedan University of Medical Sciences, Zahedan, Iran.
Receive Date: 13 December 2017,
Revise Date: 24 January 2018,
Accept Date: 03 May 2018
Abstract
Background: Oral lichen planus (OLP) is a chronic autoimmune disease with an unknown etiology. Dentists are usually the first medical practitioners to diagnose this condition although it also affects body parts other than the oral mucosa. Several studies have reported an association between the OLP and hepatitis B and C infections. This study aimed to determine the prevalence of hepatitis B virus (HBV) antigen and hepatitis C virus (HCV) antibodies in patients with OLP compared with healthy controls. Methods: In this case‒control study, 50 patients with clinical and histopathological characteristics of OLP, and 50 age- and sex-matched healthy controls supplied serum samples (5 mL) for evaluation by ELISA. Data were analyzed using SPSS Software, version 21. Chi-square test was applied as appropriate. Results: In this study, the 50 patients with OLP (33 females and 17 males) had a mean age of 42.0 ± 14.5 years, and the 50 healthy subjects (33 females and 17 males) a mean age of 41.9 ± 13.7 years. None demonstrated any evidence of HBV antigen or HCV antibodies. Discussion: We could not detect any association between OLP and viral hepatitis. This could be attributed to a lower prevalence of hepatitis viruses compared to other countries or genotypic variation or other etiological factors contributing in our cases.
Top