Cancer Incidence in Kerman Province, Southeast of Iran: Report of an ongoing Population-Based Cancer Registry, 2014

Document Type: Research Articles

Authors

1 Gastroenterology and Hepatology Research Center, Kerman University of Medical Sciences, Kerman, Iran.

2 Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran.

3 Kerman Population-Based Cancer Registry Program, Deputy of Health,, Kerman University of Medical Sciences, Kerman, Iran.

4 Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Abstract

Introduction: The epidemiology of common cancers in Kerman province, southeast of Iran, was assessed based
upon results of the Kerman Population-Based Cancer Registry Program (KPBCR). Methods: in this retrospective study,
all patients diagnosed with primary cancers and registered with the KPBCR were included. New cancer cases registered
from 2014 were identified from pathological labs, medical reports of 48 health facilities providing cancer diagnosis or
treatment services and the national death registry program. Data for patients who were referred to neighboring provinces
to access health services were also collected from national referral registries. Results from autopsies was additionally
extracted from regional forensic and legal medicine centers and added to the registry periodically. Age standardized
incidence rates (ASRs) per 100,000 person-years for all cancers were computed, using direct-standardization and CanReg
methodology. Mortality to incidence (M:I) ratios and microscopically verified (MV) proportions were calculated as
quality measures. Results: A total of 2,838 cases of cancer were registered in Kerman province, 2014. Of these 45. 6%
involved women (n=1,293). Individuals aged 60-64 years represented the largest proportion (11.6%) of the total cancer
prevalence, followed by those aged 55-59 years (10.86%) and 65-69 years (8.99%). The ASRs for all cancers were
155.1 and 118.90 per 100,000, in men and women, respectively. In women, breast (ASR: 26.4), skin (ASR: 13.0),
thyroid (ASR: 9.2), leukemia (ASR: 8.0) and colorectal (ASR: 7.70) were the most common cancers. In men, bladder
(ASR: 24.70), skin (ASR: 16.80), lung (ASR: 14.6), leukemia (ASR: 14.50), and stomach (ASR: 10.8) were found to
be the most frequent. Conclusion: This study provided latest evidence on epidemiology of cancer in the southeast of
Iran that could be used to empower prevention and control interventions in a developing country.

Keywords

Main Subjects