Document Type : Research Articles
Department of Preventive Oncology, Dr B.R.Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Department of Radiation Oncology, Christian Medical College, Ludhiana, India.
Department of Obstetrics and Gynecology, Maulana Azad Medical College, New Delhi, India.
The Hormel Institute-University of Minnesota, Austin, MN, USA.
Department of Oncoanaesthesia and Palliative Medicine, Dr B.R.Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Department of Obstetrics and Gynecology, Christian Medical College, Ludhiana, India.
Department of General Surgery, Christian Medical College, Ludhiana, India.
Department of Radiation Oncology, Manipal Hospital, Jaipur, India.
Department of Radiation Oncology, Dr B.R.Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Background: Carcinoma cervix is the second most common type of cancer in the world. With the increasing
proportion of women surviving carcinoma of the cervix, quality of life has been an important clinical issue. Since
there are very few studies from India, this study is to assess urinary dysfunction issues in patients of carcinoma cervix
treated with multimodality therapy using the LENT SOMA scores. Methods: The study was prospective and patients
treated between 1995 - 2007 on follow up were included in this study after ethical clearance. A total of 85 patients
were accrued comprising 6 stage IB, 6 stage II A, 25 stage II B, 2 stage IIIA, 45 stage III B and 1 stage IV A disease.
Sixty-six patients were treated with radiotherapy in which 46 patients received chemoradiotherapy and 19 had surgery
prior to post-operative radiotherapy. The mean age was 47.81 years with a range of 25-68 years. Completion of LENT
SOMA scale and Statistical analysis was done. Results: Mean score for BU (Bladder/Urethra) was highest (0.0758) in
fifth year of treatment whereas UK (Ureter/Kidney score was highest (0.0408) after 4 years. Bladder score was more in
60-69 years of age and in stage IIIB patients of cervical cancers. Bladder morbidity was more in patients who received
chemoradiotherapy and in patients who received radiotherapy with boost where Bladder and Urethra morbidity was more
in patients who were treated with Extended Field radiation. Conclusions: The LENT SOMA system was acceptable
and feasible to use and gave us an insight into the morbidity in our patients and to develop effective management plans
to reduce the post treatment symptoms and improve quality of life.