Document Type: Research Articles
Gastrointestinal and Liver Diseases Research Center (GILDRC), Iran University of Medical Sciences (IUMS), Tehran, Iran.
Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Firoozgar Hospital, FCRDC, Iran University of Medical Sciences, Tehran, Iran.
Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Background: Vitamin D and Calcium have a possible protective impact versus rectal neoplasm. Vitamin D, an
important nutrient, is vital to regulate the absorption of calcium and bone mineralization; nevertheless, in a case-control
study in Iran, we investigated the relationship among the dietary intake of vitamin D and calcium with the hazard of
rectal neoplasm. Methods: 363 subjects (162 cases and 201 controls) participated in the case- control Study from
March 2017 to November 2018. Dietary intake of Calcium and Vitamin D was calculated using a 148-items foodfrequency
questionnaire. Results: Since altering the strong confounding agents, the multivariate risk proportion within
the dietary vitamin D intake was OR=0.2, 95%CI 0.1-0.5, P_value case of calcium and rectal cancer. Conclusions: Taken together, a possible reduction in the hazard of rectal neoplasm
with dietary intake of Vitamin D within Iranian patients was observed.