Document Type : Research Articles
Hematology Unit, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
Medical Oncology Unit, Mansoura University Oncology Center (MUOC) Mansoura University, Egypt.
Hematology Unit, Mansoura University Oncology Center (MUOC), Mansoura University, Egypt.
Objectives: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia. Methods: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR. Results: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p