Breast cancer is a common cancer found among women worldwide. Many polymorphisms can play a role in the development of this disease. The study was conducted to evaluate whether 2R/3R and 6bp insertion/deletion polymorphisms of the TYMS gene are associated with breast cancer risk in the Kurdish Iraqi population. Materials and Methods: DNA was extracted from EDTA-treated peripheral blood samples and included 100 patients affected by breast cancer and 100 controls. Genotyping was performed by PCR-electrophoresis. Results: Our results showed a significant association between 6bp deletion homozygote genotype in breast cancer patients compared to healthy individuals (P = 0.042). No significant differences were observed for other allelic and genotypic frequencies. Conclusion: This study, performed for the first time on the Kurdish population, highlighted the need for further studies of the TYMS gene polymorphisms.
Mohamad, K. (2021). Association between 5’-UTR and 3’-UTR Polymorphisms of the TYMS Gene and Breast Cancer in Kurdish Women of Iraq. Asian Pacific Journal of Cancer Prevention, 22(5), 1557-1560. doi: 10.31557/APJCP.2021.22.5.1557
MLA
Kazhal Shekh Mohamad. "Association between 5’-UTR and 3’-UTR Polymorphisms of the TYMS Gene and Breast Cancer in Kurdish Women of Iraq". Asian Pacific Journal of Cancer Prevention, 22, 5, 2021, 1557-1560. doi: 10.31557/APJCP.2021.22.5.1557
HARVARD
Mohamad, K. (2021). 'Association between 5’-UTR and 3’-UTR Polymorphisms of the TYMS Gene and Breast Cancer in Kurdish Women of Iraq', Asian Pacific Journal of Cancer Prevention, 22(5), pp. 1557-1560. doi: 10.31557/APJCP.2021.22.5.1557
VANCOUVER
Mohamad, K. Association between 5’-UTR and 3’-UTR Polymorphisms of the TYMS Gene and Breast Cancer in Kurdish Women of Iraq. Asian Pacific Journal of Cancer Prevention, 2021; 22(5): 1557-1560. doi: 10.31557/APJCP.2021.22.5.1557
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