Breast Cancer Incidence in Kyrgyzstan: Report of 15 Years of Cancer Registry

Document Type : Research Articles

Authors

1 International Higher School of Medicine, Bishkek, Kyrgyzstan Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan.

2 International Higher School of Medicine, Bishkek, Kyrgyzstan.

3 Kyrgyz State Medical Academy named after I. K. Akhunbaev, Bishkek, Kyrgyzstan, Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan.

4 National Center for Oncology and Hematology, Bishkek, Kyrgyzstan Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan.

5 Khoja Akhmet Yassawi International Kazakh- Turkish University, Shymkent Campus, Kazakhstan.

6 Astana Medical University, Nur-Sultan, Kazakhstan Central Asian Institute for Medical Research, Nur-Sultan, Kazakhstan Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan.

7 Kyrgyz-Russian Slavic University, Bishkek, Kyrgyzstan, International Higher School of Medicine, Bishkek, Kyrgyzstan.

8 Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan, Astana Medical University, Nur-Sultan, Kazakhstan, Central Asian Cancer Institute, Nur-Sultan, Kazakhstan.

Abstract

Objective: The epidemiological features of the breast cancer (BC) incidence in Kyrgyzstan were studied. Methods: The retrospective study (2003-2017). Descriptive and analytical methods of oncoepidemiology were used. Crude (CR), age-specific (ASIR), age-standardized (ASR), equalized incidence rates and approximation were calculated. The method of drawing up a cartogram based on the determination of the standard deviation (σ) from the mean (x) was applied. Results: During the study period, 7,850 new cases of BC were registered. The average annual crude and age-standardized incidence rate were 18.8±0.5 and 24.0±0.5 cases per 100,000 population of female, respectively, and their trends tended to increase (Т=+1.0%; R2=0.242 and Т=+0.2%; R2=0.015, respectively). The analysis of ASIR showed unimodal growth with a peak at 60-64 years – 85.9±4.9 cases per 100,000 population of female. ASIR trends decreased in the age groups of 40-59 years, and the most pronounced decrease was in 50-54 years (T=−1.5%; R2=0.391), in other age groups the trend increased and were most pronounced up to 30 years (T=+4.4%; R2=0.180). Trends in ASR of BС tended to grow in almost all regions, with higher levels in Osh (Т=+3.6%; R2=0.665) and Jalal-Abad (Т=+3.8%; R2=0.551) regions. The cartograms of ASR per 100,000 population of female were allocated according to the following criteria: low – up to 17.2, average – from 17.2 to 26.5, high – above 26.5. The results of the spatial analysis showed the regions with a higher levels of BC incidence rate per 100,000 population of female: Chuy (31.3), Osh city (27.1) and Bishkek city (39.2). Conclusion: The study of the epidemiological spatio-temporal features of the incidence of breast cancer is of both theoretical and practical interest and plays an important role in monitoring and evaluating anticancer activities.

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Volume 23, Issue 5
May 2022
Pages 1603-1610
  • Receive Date: 19 September 2021
  • Revise Date: 19 March 2022
  • Accept Date: 09 May 2022
  • First Publish Date: 09 May 2022