Validation of the Thai Version of the Memorial Symptom Assessment Scaled - Short Form Among Cholangiocarcinoma Patients

Document Type : Research Articles


1 Faculty of Nursing, Western University, Buriram, Thailand.

2 Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.

3 Faculty of Nursing, Udon Thani Rajabhat University, Thailand.

4 Faculty of Nursing, Ratchathani University, (Udon Thani Campus), Thailand.


Background: The Memorial Symptom Assessment Scale-Short Form (MSAS-SF), a standard instrument for assessing cancer patients’ symptoms, has been validated in numerous languages. However, it has not been validated in Thai. Objectives: The purpose of this study was to translate the MSAS-SF into Thai and determine its psychometric properties in Cholangiocarcinoma (CCA) patients. Methods: The MSAS-SF was translated into Thai, and 231 CCA patients completed the questionnaires, which included baseline characteristics, T-MSAS-SF, Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep), and the Hospital Anxiety and Depression Scale (HADS). Cronbach’s alpha coefficient was used to assess reliability for internal consistency. For convergent validity, Pearson’s correlation coefficient was used to calculate the relationship between the T-MSAS-SF and the T-CaSUN, HADS, and FACT-Hep subscales. Results: Subscale and total T-MSAS-SF internal consistency reliability was moderately high, with Cronbach alpha coefficients ranging from 0.76 to 0.87. For convergent validity, the majority of T-MSAS-SF scores had moderate to low inverse correlation with FACT-Hep, HADS T-CaSUN subscales with the correlation coefficients-0.10 to -0.68 (p<0.05), reflecting that they were measuring a similar construct.Conclusion: Our findings showed that the T-MSAS-SF has acceptable validity and reliability to assess the psychometric properties of early to advance stage CCA patients during treatment and early post-treatment stage.


Main Subjects

Volume 23, Issue 11
November 2022
Pages 3851-3857
  • Receive Date: 25 June 2022
  • Revise Date: 23 August 2022
  • Accept Date: 17 November 2022
  • First Publish Date: 17 November 2022