%0 Journal Article %T Locally Advanced Breast Cancer in Jamaica: Prevalence, Disease Characteristics and Response to Preoperative Therapy %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2014 %\ 07/01/2014 %V 15 %N 7 %P 3323-3326 %! Locally Advanced Breast Cancer in Jamaica: Prevalence, Disease Characteristics and Response to Preoperative Therapy %K breast cancer %K locally advanced breast cancer %K Neoadjuvant chemotherapy %K preoperative chemotherapy %R %X Breast cancer is the most common cancer in Jamaican women. Locally advanced breast cancer (LABC) isassociated with aggressive biology and poor prognosis, and has a predilection for African-American women. Inthis retrospective review, we assessed the prevalence of LABC as a breast cancer presentation in a population ofmainly Afro-centric ethnicity, and determined disease characteristics and response to pre-operative chemotherapy.LABC was prevalent (20%), and had a low pathological response rate to pre-operative chemotherapy, with ahigh risk of disease recurrence. Increased utilization of breast cancer screening may help detect cancer at lessadvanced stages, and optimizing pre-operative chemotherapy is recommended to improve response rates andultimately survival. %U https://journal.waocp.org/article_29081_e72b66e864535abf56b050c98591356c.pdf