West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. Asian Pacific Journal of Cancer Prevention 1513-7368 13 9 2012 09 01 Clinical Study on Safety and Efficacy of Qinin® (Cantharidin Sodium) Injection Combined with Chemotherapy in Treating Patients with Gastric Cancer 4773 4776 26929 EN Journal Article 1970 01 01 <br/><b>Objectives</b>: To assess the efficacy, side effects, and the impact on quality of life with Qinin® (Cantharidinsodium) injection combined with chemotherapy for gastric cancer patients. <br/><b>Method</b>: A consecutive cohort of 70patients were divided into two groups: experimental group with cantharidin sodium injection combined withchemotherapy, while the control group received chemotherapy alone. After more than two courses of treatment,efficacy, quality of life and side effects were evaluated. <br/><b>Results</b>: The response rate of experimental group wasnot significantly different from that of the control group (P>0.05), but differences were significant in clinicalbenefit response and KPS score. In addition, gastrointestinal reactions and the incidence of leukopenia werelower than in the control group (P<0.05). <br/><b>Conclusions</b>: Qinin® (Cantharidin sodium) injection combined withchemotherapy enhances clinical benefit response, improving quality of life of gastric cancer patients and reducingside effects of chemotherapy. Thus Qinin® (Cantharidin sodium) injection deserves to be further investigatedin randomized control clinical trails. https://journal.waocp.org/article_26929_cb0f826ef1ba64a98b48513aeb885b73.pdf