West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. Asian Pacific Journal of Cancer Prevention 1513-7368 18 8 2017 08 01 Role of Multidetector Computed Tomography in Evaluation of Ovarian Lesions in Women Clinically Suspected of Malignancy 2059 2062 49597 10.22034/APJCP.2017.18.8.2059 EN Shazia Mukhtar Dow Institute of Radiology, Dow University of Health Sciences, Karachi, Pakistan Sohail Ahmed Khan Dow Institute of Radiology, Dow University of Health Sciences, Karachi, Pakistan Munawar Hussain Dow Institute of Radiology, Dow University of Health Sciences, Karachi, Pakistan Syed Omair Adil Dow Institute of Radiology, Dow University of Health Sciences, Karachi, Pakistan Journal Article 2016 12 21 Objective: To determine the diagnostic accuracy of multidetector computed tomography (MDCT) in the evaluation of ovarian carcinoma using histopathology as the gold standard. Methods: This prospective cross-sectional study was conducted at Department of Radiology, Dow international medical college, DUHS, Karachi from December 2015 to April 2016. All patients of 30-60 years of age who were referred for CT a scan of the abdomen and pelvis with clinical suspicion of malignant ovarian cancer were included. A total of 158 cases were assessed with signs and symptoms of weight loss and an abdominal or pelvic mass detected on examination by a physician. Results: The mean age was 42.7 ±10.3 years (range 30-60). The largest group (46, 29.1%) presented with Stage 0 disease. The mean duration of symptoms was 4.06 ±1.39 months (range 1-6). Taking histopathology as the gold standard the sensitivity, specificity, NPV, PPV and overall diagnostic accuracy values for MDCT were 95.6%, 97.3%, 93.5%, 97.3% and 96.8%, respectively. Conclusion: MDCT showed high accuracy in differentiating benign and malignant lesions and as well as staging of malignant cases which should be very helpful in management of ovarian disease.

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