West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. Asian Pacific Journal of Cancer Prevention 1513-7368 19 10 2018 10 01 Comparision of Different Radiotherapy Planning Techniques for Breast Cancer after Breast Conserving Surgery 2929 2934 67431 10.22034/APJCP.2018.19.10.2929 EN Narudom Supakalin Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Montien Pesee Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Komsan Thamronganantasakul Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. 0000-0002-6809-8855 Kiattisak Promsensa Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Chunsri Supaadirek Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Srichai Krusun Division of Radiotherapy, Department of Radiology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Journal Article 2018 05 17 Objectives:To compare different radiotherapy planning techniques for breast cancer after breast conserving surgery.<br />Materials and methods: Eighteen patients with breast cancer who underwent breast conserving surgery were selected.<br />For each patient four different whole breast irradiation techniques including Tan, fIMRT, iIMRT and VMAT were<br />compared to the conventional tangential technique (Tan). Results: Mean maximum point dose (Dmax) for Tan, fIMRT,<br />iIMRT and VMAT were 110.17% (±1.87), 105.89% (±1.13), 106.47% (±0.92) and 106.99% (±1.16) (p<0.001). Mean<br />minimum point dose (Dmin) from Tan was 84.02% (±3.68) which was significantly higher than those from fIMRT,<br />iIMRT and VMAT which were 76.57% (±11.4), 67.69 %( ±19.20) and 80.69% (±7.06) (p<0.001). Only the mean<br />V95 of fIMRT was significantly less than Tan (p=0.01). Mean percentage of volume receiving ≥ 20 Gy (V20Gy) and<br />mean doses of the ipsilateral lung were 17.09% and 953.05 cGy, 16.60% and 879.20 cGy, 14.79% and 772.26 cGy,<br />15.32% and 984.34 cGy for Tan, fIMRT, iIMRT and VMAT. Only iIMRT had a significantly lower mean V20Gy and<br />the mean dose to ipsilateral lung in comparison with Tan. Significantly, high mean doses to the contralateral breast<br />(498.07 cGy, p<0.001) were observed in VMAT. Conclusion: The conventional tangential technique provides adequate<br />dose coverage but resulted in high dose-volumes. The iIMRT and fIMRT had significantly smaller high dose-volumes<br />and better conformity. VMAT demonstrated excellent dose homogeneity and conformity but an increased low-dose<br />volume outside the target should be of concern. https://journal.waocp.org/article_67431_2d91645c7c05cd95e256c4ccaf45c631.pdf