Transcriptome-wide Network Analysis of Squamous Lung Cancer Reveals Potential Methylation Genes


Lung cancer is a prevalent cancer with a high death rate. Underlying mechanisms havebeen found to be highly correlated with epigenetics, especially with DNA methylation. With methylation array and other regulation data, we constructed a TF-gene regulation network and a TF-pathway network. Through those networks, we identified lung cancer related genes that were found by previous studies, and supposed a number of new examples. Our work demonstrated the new potential methylation for lung cancer.