Evaluation of Safety and Side Effects COVID-19 Vaccine in Cancer Patients Being Treated

Document Type : Research Articles


1 Department of Internal Medicine, Talaghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

2 Clinical Research Department Center, Imam Reza Hospital, Kermanshah University of Medical Science, Kermanshah, Iran.

3 Talaghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.


According to the instructions of Iran’s National Corona Response Committee in the Iranian Ministry of Health and Medical Education, patients undergoing treatments for their cancer are prioritized in Covid-19 vaccination. The present study was therefore conducted to investigate the toxicity and acute side-effects of a Covid-19 vaccine in cancer patients presenting to Medical Oncology Clinic of Kermanshah University of Medical Science. After excluding the patients with active infection and the recently-infected ones with Covid-19, they underwent the vaccination. The patients with cell counts exceeding 3,000 received two doses of the vaccine with a 21-day interval and treatment of their underlying disease was postponed for 7 days. The side-effects were mild and tolerable and included fever (case 10), pain at the injection site (7), dizziness (7), body pain (6), abdominal pain (6), myalgia (6), headache (6), chills (3), shortness of breath (3), diarrhea (1), runny nose (1) and dryness of the throat (1). No significant toxicity was reported in the patients who were safely vaccinated under the supervision of the medical oncology clinic. 


Main Subjects

Volume 23, Issue 4
April 2022
Pages 1263-1270
  • Receive Date: 15 October 2021
  • Revise Date: 18 February 2022
  • Accept Date: 13 April 2022
  • First Publish Date: 13 April 2022