Document Type : Research Articles
Department of Medicine, Neuchâtel Hospital, Neuchâtel, Switzerland.
Specialized Education and Training Support Service, Health Promotion and prevention in Schools, Community Health Department of the Canton of Vaud, Lausanne, Vaud, Switzerland.
Service of Pediatrics, Department Woman Mother Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Service of Gynecology and Obstetrics, Lausanne University Hospital, Lausanne, Switzerland.
Unit of Pediatric Infectious Diseases and Vaccinology, Department Women Mother Child, Lausanne University, Hospital and University of Lausanne, Lausanne, Switzerland.
Background: Switzerland, with an adolescent HPV vaccination coverage at 59%, remains far from reaching the crucial swiss national goal of 80% coverage. Our objective was to implement a new information brochure in schools to increase HPV vaccination uptake. Methods: We designed a public health quality project. A new information brochure was produced and was distributed to a test group of 9th grade students from the Canton of Vaud, in Switzerland during the 2019-2020 school year. Vaccine uptake of the test group was compared to those of all other students in 2019-2020 and of students in the same schools in 2017-2018. Results: 12,143 electronic records were analyzed. 713 students were enrolled in 6 schools where the new brochure was distributed. Median age was 13 years (IQR 12-13), and 6,031 (49.7%) were female. Vaccine uptake was 52% (6,299/12,143). The new brochure did not result in increased uptake. Age ≥ 13 years (aOR 1.39, 95% CI 1.22-1.58) was significantly associated with uptake. Uptake increased between 2017-2018 (51%, 3,216/6,307) and 2019-2020 (52.8%, 3,083/5,836, p=0.04) due to increased acceptance among boys. The only determinant of uptake in 2019-2020 was uptake in the same schools in 2017-2018. Conclusion: The introduction of a new information brochure was insufficient to increase HPV vaccination coverage. More innovative strategies are needed.