Objective: Seeking information about cancer is an important means by which individuals acquire cancerrelatedknowledge and know whether they should be screened for cancer. This study was performed to identifythe desired types of cancer screening information and to describe patterns of information-seeking behavior. Methods: In August 2006, a questionnaire was administered to a population of South Korean adults who rangedin age from 40 to 70 years (n = 1,676). The chi-square test, linear regression, and logistic regression were usedfor data analysis. Results: Only 7.8% of the study population reported seeking information about cancer withinthe previous 12 months. Respondents were more likely to seek information about cancer if they were youngerthan 49 years, had a post-high school education, were insured through Medicaid, perceived their health statusto be fair or poor/very poor and had received prior cancer screening. The most desired information includedmethods of cancer screening, followed by procedures, benefits and necessity, and limits and side effects. Factorsassociated with the need for information were age (i.e., less than 49 years), residence (i.e., non-metropolitan),perceived health status (i.e., fair or poor/very poor), cancer family history, and prior cancer screening. Conclusion:It is important to understand the characteristics of information seekers and non-seekers and to deliver cancerscreening information based on individuals’ needs to promote higher rates of cancer screening.