Chemoprevention is one feasible approach to decreasing morbidity and mortality of non-small cell lungcancer (NSCLC). The present study aimed to explore the mechanisms of chemoprevention of NSCLC by Prunellavulgaris L. (PV) using a PV extract of 60% ethanol (P-60). In an A/J mouse model benzo[a]pyrene induction oflung tumors was significantly reduced difference by P-60 group. In addition, P-60 was found to have the abilityto regulate cell cycle and induce apoptosis in SPC-A-1 cells. Therefore, we propose that P-60 has potential as alung cancer chemopreventive agent.
(2010). Chemoprevention by Prunella vulgaris L. Extract of Non-Small Cell Lung Cancer Via Promoting Apoptosis and Regulating the Cell Cycle. Asian Pacific Journal of Cancer Prevention, 11(5), 1355-1358.
MLA
. "Chemoprevention by Prunella vulgaris L. Extract of Non-Small Cell Lung Cancer Via Promoting Apoptosis and Regulating the Cell Cycle". Asian Pacific Journal of Cancer Prevention, 11, 5, 2010, 1355-1358.
HARVARD
(2010). 'Chemoprevention by Prunella vulgaris L. Extract of Non-Small Cell Lung Cancer Via Promoting Apoptosis and Regulating the Cell Cycle', Asian Pacific Journal of Cancer Prevention, 11(5), pp. 1355-1358.
VANCOUVER
Chemoprevention by Prunella vulgaris L. Extract of Non-Small Cell Lung Cancer Via Promoting Apoptosis and Regulating the Cell Cycle. Asian Pacific Journal of Cancer Prevention, 2010; 11(5): 1355-1358.
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