Background: Some studies have indicated a protective role of H.pylori against risk of esophageal squamouscell carcinoma (ESCC). The purpose of this study was to explore this possible relationship in a case-controlstudy. Methods: One hundred consecutive patients diagnosed with ESCC and 100 healthy people were enteredwith informed consent. All were asked to provide a blood sample and serum immunoglobulin G (IgG) antibodiesagainst HP-CSAs were measured with an enzyme-linked immunosorbent assay (ELISA). Results: There wassignificant reverse association between H. pylori positivity and tumour development (OR=0.28, 95% CI: 0.15-0.54), but not with a Cag A positive status. Conclusion: Our findings provide further evidence that H. pyloriinfection decreases the risk of ESCC but that this is not linked to a Cag A positive status.
(2011). Helicobacter Pylori Infection Reduces the Risk of Esophageal Squamous Cell Carcinoma: A Case-Control Study in Iran. Asian Pacific Journal of Cancer Prevention, 12(1), 149-151.
MLA
. "Helicobacter Pylori Infection Reduces the Risk of Esophageal Squamous Cell Carcinoma: A Case-Control Study in Iran". Asian Pacific Journal of Cancer Prevention, 12, 1, 2011, 149-151.
HARVARD
(2011). 'Helicobacter Pylori Infection Reduces the Risk of Esophageal Squamous Cell Carcinoma: A Case-Control Study in Iran', Asian Pacific Journal of Cancer Prevention, 12(1), pp. 149-151.
VANCOUVER
Helicobacter Pylori Infection Reduces the Risk of Esophageal Squamous Cell Carcinoma: A Case-Control Study in Iran. Asian Pacific Journal of Cancer Prevention, 2011; 12(1): 149-151.