Synchronous Primary Cancers of the Female Reproductive Tract in Turkish Women

Objectives: To evaluate the synchronous gynecologic cancers in Turkish women. Materials and methods: Apopulation-based longitudinal cohort study was conducted using Izmir Cancer Registry (ICR) data on gynecologiccancer patients diagnosed in the period 1993 to 2005. The registry covers the 3.7 million population of Izmir andhas been collecting data on cancer incidence and survival of cancer patients’ since 1992. The ICR collects data onall new cases of cancer from all the hospitals (n = 22) in the city.
Results: A total of 4,185 women were identifiedwith gynecologic cancer between 1993 and 2005, 1,526 with endometrial, 1,206 with cervical, 1,198 with ovarian,115 with vulvar, 67 with other uterine ( sarcoma etc.), 33 with vaginal and 40 with other gynecologic cancers (tuba uterina etc.). Fifty-five (1.3%) patients with invasive synchronous primary cancers were identified, 43 ofthese tumor pairs being endometrium-ovaries (81%), 66 of all lesions being endometrioid adenocarcinomas.
Conclusions: Independent primary tumors of the endometrium and ovary are the most commonly encounteredsynchronous tumors of the female genital tractus with endometrioid adenocarcinoma as the most frequentcomponent.