Comparison of Complications of Peripherally Inserted Central Catheters with Ultrasound Guidance or Conventional Methods in Cancer Patients

Objective: To compare the complications of peripherally inserted central catheters (PICC) by a modifiedSeldinger technique under ultrasound guidance or the conventional (peel-away cannula) technique.
Methods:From February to December of 2010, cancer patients who received PICC at the Department of Chemotherapyin Jiangsu Cancer Hospital were recruited into this study, and designated UPICC if their PICC lines wereinserted under ultrasound guidance, otherwise CPICC if were performed by peel-away cannula technique. Therates of successful placement, hemorrhage around the insertion area, phlebitis, comfort of the insertion arm,infection and thrombus related to catheterization were analyzed and compared on days 1, 5 and 6 after PICCand thereafter.
Results: A total of 180 cancer patients were recruited, 90 in each group. The rates of successfulcatheter placement between two groups differed with statistical significance (P <0.05), favoring UPICC. Morephlebitis and finger swelling were detected in the CPICC group (P <0.05). From day 6 to the date the catheterwas removed and thereafter, more venous thrombosis and a higher rate of discomfort of insertion arms were alsoobserved in the CPICC group.
Conclusion: Compared with CPICC, UPICC could improve the rate of successfulinsertion, reduce catheter related complications and increase comfort of the involved arm, thus deserving to befurther investigated in randomized clinical studies.