Clinical Study on Safety and Efficacy of Qinin® (Cantharidin Sodium) Injection Combined with Chemotherapy in Treating Patients with Gastric Cancer

Objectives: To assess the efficacy, side effects, and the impact on quality of life with Qinin® (Cantharidinsodium) injection combined with chemotherapy for gastric cancer patients.
Method: A consecutive cohort of 70patients were divided into two groups: experimental group with cantharidin sodium injection combined withchemotherapy, while the control group received chemotherapy alone. After more than two courses of treatment,efficacy, quality of life and side effects were evaluated.
Results: The response rate of experimental group wasnot significantly different from that of the control group (P>0.05), but differences were significant in clinicalbenefit response and KPS score. In addition, gastrointestinal reactions and the incidence of leukopenia werelower than in the control group (P<0.05).
Conclusions: Qinin® (Cantharidin sodium) injection combined withchemotherapy enhances clinical benefit response, improving quality of life of gastric cancer patients and reducingside effects of chemotherapy. Thus Qinin® (Cantharidin sodium) injection deserves to be further investigatedin randomized control clinical trails.