A Comment to the Article Published in the APJCP by Choi and Co-workers about the Treatment of Cancer with Citric Acid

I first published the medical hypothesis that citric acid,as a natural inhibitor of glycolysis, would be effective asa cancer treatment in March, 2007 (Halabe Bucay, 2007).Two years and two months later, on May, 2009, I publishedin the same journal the first case of a patient with cancerwho improved only with citric acid as antineoplastictreatment, a 12 years old boy who had terminal medullarythyroid cancer as part of a multiple endocrine neoplasia(Halabe Bucay, 2009). Nine months later, in February,2011, data for a second patient with terminal cancer,peritoneal mesothelioma who improved again only withcitric acid, were published (Bucay, 2011). The hypothesisthat citric acid is effective as a cancer treatment hasbeen demonstrated with these 2 unquestionable cases(Halabe Bucay, 2009; Bucay, 2011), and there is a lot ofinformation in internet, available for everyone to access.Therefore, perhaps, the patients reported in the articlefrom Korea (Choi et al., 2012) knew this information andthat this is an explanation for their improvement of cancerstatus.