Clinicopathological Features and Localization of Gastric Cancers and their Effects on Survival in Turkey

Background: This study was designed to examine changing trends in localization of gastric cancer in Turkeyin recent years. Materials and
Methods: A total of 796 adult patients with newly diagnosed, histologicallyproven adenocarcinomas, treated and followed up at our oncology center between 2000-2011, were examinedretrospectively. In all cases tumor localization were identified and recorded with clinicopathological features.
Results: The median age was 58 with a range between 22-90 for the 552 men and 244 women. Median followup was 12 months (1-276) and median overall survival was also 12 months (11.5-12.4). There was a trend for achange in tumor localization from distal to proximal. Survival of patients was low with advanced T and N stagetumours. Positive surgical margins, lymphovascular invasion, perineural invasion, cardioesophageal localizationwere predisposition factors for metastatic disease in gastric cancer. There was no relation between age or sexand histopathological type of gastric cancer.
Conclusions: There is a trend in our country for a change in gastrictumour localization from distal to proximal, with clear significance for treatment choices.