Curcumin previously was proven to inhibit angiogenesis and display potent antitumor activity in vivo andin vitro. In the present study, we investigated whether a combination curcumin with hyperthermia would havea synergistic antitumor effect in the LL/2 model. The results indicated that combination therapy significantlyinhibited cell proliferation of MS-1 and LL/2 in vitro. LL/2 experiment model also demonstrated that thecombination therapy inhibited tumor growth and prolonged the life span in vivo. Furthermore, combinationtherapy reduced angiogenesis and increased tumor apoptosis. Our findings suggest that the combination therapyexerted synergistic antitumor effects, providing a new perspective fpr clinical tumor therapy.
(2013). Enhanced Antitumor Effect of Curcumin Liposomes with Local Hyperthermia in the LL/2 Model. Asian Pacific Journal of Cancer Prevention, 14(4), 2307-2310.
MLA
. "Enhanced Antitumor Effect of Curcumin Liposomes with Local Hyperthermia in the LL/2 Model". Asian Pacific Journal of Cancer Prevention, 14, 4, 2013, 2307-2310.
HARVARD
(2013). 'Enhanced Antitumor Effect of Curcumin Liposomes with Local Hyperthermia in the LL/2 Model', Asian Pacific Journal of Cancer Prevention, 14(4), pp. 2307-2310.
VANCOUVER
Enhanced Antitumor Effect of Curcumin Liposomes with Local Hyperthermia in the LL/2 Model. Asian Pacific Journal of Cancer Prevention, 2013; 14(4): 2307-2310.
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