The RAS family genes encode small GTP-binding cytoplasmic proteins. Activated KRAS engages multipleeffector pathways, notably the RAF-mitogen-activated protein kinase, phosphoinositide-3-kinase (PI3K) andRalGDS pathways. In the clinical field, K-ras oncogene activation is frequently found in human cancers and thusmay serve as a potential diagnostic marker for cancer cells in circulation. This mini-review aims to summariseinformation on Ras-induced oncogenesis and the clinical significance of K-ras.
(2013). Oncogenesis and the Clinical Significance of K-ras in Pancreatic Adenocarcinoma. Asian Pacific Journal of Cancer Prevention, 14(5), 2699-2701.
MLA
. "Oncogenesis and the Clinical Significance of K-ras in Pancreatic Adenocarcinoma". Asian Pacific Journal of Cancer Prevention, 14, 5, 2013, 2699-2701.
HARVARD
(2013). 'Oncogenesis and the Clinical Significance of K-ras in Pancreatic Adenocarcinoma', Asian Pacific Journal of Cancer Prevention, 14(5), pp. 2699-2701.
VANCOUVER
Oncogenesis and the Clinical Significance of K-ras in Pancreatic Adenocarcinoma. Asian Pacific Journal of Cancer Prevention, 2013; 14(5): 2699-2701.
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