Objectives: To study variation in T lymphocyte subgoups and its clinical significance in non-small cell lungcancer (NSCLC). Methods: Levels of CD3+ , CD4+ , CD8+ , CD4+/CD8+, NK and Treg cells in peripheral bloodof NSCLC cases and healthy adults were determined by flow cytometry. Results: CD3+ , CD4+ and CD4+/CD8+ratio and NK cells in NSCLCs were decreased significantly in comparison with the control group (P < 0.01), anddecreased with increase in the clinical stage of NSCLC, while CD8+ cells demonstrated no significant change(P > 0.05). Treg cells were significantly more frequent than in the control group (P < 0.01), and increased withthe clinical stage of NSCLC. Conclusion: The cellular immune function of the NSCLC patients is lowered. Itis important to detect change of T lymphocyte subgroups by flow cytometry for the diagnosis, treatment andprognostic assessment of NSCLC patients.
(2013). Variation of Blood T Lymphocyte Subgroups in Patients with Non- small Cell Lung Cancer. Asian Pacific Journal of Cancer Prevention, 14(8), 4671-4673.
MLA
. "Variation of Blood T Lymphocyte Subgroups in Patients with Non- small Cell Lung Cancer". Asian Pacific Journal of Cancer Prevention, 14, 8, 2013, 4671-4673.
HARVARD
(2013). 'Variation of Blood T Lymphocyte Subgroups in Patients with Non- small Cell Lung Cancer', Asian Pacific Journal of Cancer Prevention, 14(8), pp. 4671-4673.
VANCOUVER
Variation of Blood T Lymphocyte Subgroups in Patients with Non- small Cell Lung Cancer. Asian Pacific Journal of Cancer Prevention, 2013; 14(8): 4671-4673.