Objective: To assess the level of an inpatient population’s awareness about hepatitis and primary liver cancer(PLC), the most common type of which is hepatocellular carcinoma (HCC), and then to initiate education ofthis group. Methods: A survey was conducted with 1300 participants within the inpatient unit in representativetertiary hospitals in the Chaoshan area of China. Structured questionnaires contained demographic data andstatements about different aspects of liver cancer and hepatitis. The questionnaires were completed by trainedmedical practitioners after they had conducted the interviews. Results: One way ANOVA showed that thesample population lacked adequate knowledge about HCC and hepatitis. Stepwise multiple regression analysisdemonstrated that the participant’s level of education had the greatest impact on their total knowledge scorewhen other variables remained constant. Conclusions: The study demonstrated: a general lack of awarenessamongst the participants about the preventative strategies, and the management options available for peoplewith primary liver cancer and hepatitis; education level was an important factor affecting knowledge levels.The demonstrated deficiencies in people’s knowledge about hepatitis and HCC, and their lack of subsequentprotective behaviours are likely to play an important role in HCC and hepatitis transmission or prevention.