Surgical Outcomes of Patients with Stage IA2 Cervical Cancer Treated with Radical Hysterectomy

Background: This study was undertaken to evaluate the surgical outcomes of patients with stage IA2 cervicalcancer treated with radical hysterectomy. Data for 58 patients who underwent modified radical hysterectomyor radical hysterectomy with pelvic lymphadenectomy between January 2003 and December 2012 at ChiangMai University Hospital were retrospectively reviewed. The analysis included clinico-pathological risk factors(nodal metastasis, parametrial involvement), adjuvant treatment, 5-year disease-free survival and 5-year overallsurvival. All pathologic slides were reviewed by a gynecologic pathologist. Follow-up methods included at leastcervical cytology and colposcopy with directed biopsy if indicated. Univariate analysis was performed to identifyfactors associated with median survival. At the median follow up time of 73 months, the 5-year disease-freesurvival and the 5-year overall survival were 97.4% and 97.4%, respectively. Two (3.4%) patients had pelviclymph node metastases. In a univariate analysis, there was no statistically significant association between survivaland prognostic factors such as age, histological cell type, lymph-vascular space invasion, vaginal margin statusand lymph node status. Surgical and survival outcomes of women with stage IA2 cervical cancer are excellent.No parametrial involvement was detected in our study. Patients with stage IA2 cervical cancer may be treatedwith simple or less radical hysterectomy with pelvic lymphadenectomy.