Background: Testicular germ cell tumors (TGCTs) are a relatively common malignancy in young men. Theaim of this study was to investigate the clinicopathological features and survival of young Turkish patientswith TGCT. Materials and Methods: In this retrospective study, the clinical and pathological characteristics ofyoung Turkish patients with TGCT who were monitored by the Department of Medical Oncology of a militaryhospital between 2008 and 2013 were investigated. Overall survival data were analyzed. Results: Ninety-sixpatients were included in the study. The mean age was 26.4 years. Among the patients, 17.7% had seminomaand 43.8% had mixed non-seminomatous germ cell tumors. Some 46.9% were Stage I, 30.2% were Stage II, and22.9 were Stage III. Of the patients, 83.3% received chemotherapy, 25% underwent retroperitoneal lymph nodedissection (RPLND), 3.1% received radiotherapy, and 12.5% were followed-up without treatment. In addition,18.8% of the patients were administered salvage chemotherapy due to relapse or progression. The 5-year overallsurvival rate was 90.2% for all patients. The 2-year overall survival rate was 100% for Stage I patients, 94%for Stage II patients, and 70.2% for Stage III patients. The difference between the survival curves of stages wasstatistically significant (p=0.029). Conclusions: In young Turkish patients with TGCT, good results were obtainedwith appropriate treatment, most receiving chemotherapy. The prognosis of the disease was good even in theadvanced stage.
(2013). Clinicopathological Features and Survival of Young Turkish Patients with Testicular Germ Cell Tumors. Asian Pacific Journal of Cancer Prevention, 14(11), 6889-6892.
MLA
. "Clinicopathological Features and Survival of Young Turkish Patients with Testicular Germ Cell Tumors". Asian Pacific Journal of Cancer Prevention, 14, 11, 2013, 6889-6892.
HARVARD
(2013). 'Clinicopathological Features and Survival of Young Turkish Patients with Testicular Germ Cell Tumors', Asian Pacific Journal of Cancer Prevention, 14(11), pp. 6889-6892.
VANCOUVER
Clinicopathological Features and Survival of Young Turkish Patients with Testicular Germ Cell Tumors. Asian Pacific Journal of Cancer Prevention, 2013; 14(11): 6889-6892.