Background: Variation in metabolic genes is regarded as an important factor in processes leading to cancer.However, the effect of GSTT1 null genotype is divergent in the form of lung cancer. Methods: Studies wereconducted at different research databases from 1990 to 2013 and the total odds ratio (OR) and 95% confidenceinterval (CI) were calculated for lung cancer. Review Manager 5.2 and STATE 12 are employed. Results: TotalOR value is calculated from 17 articles with 2,118 cases and 2,915 controls. We discovered no significant increasein lung cancer risk among subjects carrying GSTT1 null genotype [OR = 1.15; 95% CI 0.97-1.36] in this metaanalysis. Conclusion: The GSTT1 deletion polymorphism does not have a significant effect on the susceptibilityto lung cancer overall in China.
(2013). Lack of Assocation of Glutathione S-transferase T1 Gene Null and Susceptibility to Lung Cancer in China: a Meta-analysis. Asian Pacific Journal of Cancer Prevention, 14(12), 7215-7219.
MLA
. "Lack of Assocation of Glutathione S-transferase T1 Gene Null and Susceptibility to Lung Cancer in China: a Meta-analysis". Asian Pacific Journal of Cancer Prevention, 14, 12, 2013, 7215-7219.
HARVARD
(2013). 'Lack of Assocation of Glutathione S-transferase T1 Gene Null and Susceptibility to Lung Cancer in China: a Meta-analysis', Asian Pacific Journal of Cancer Prevention, 14(12), pp. 7215-7219.
VANCOUVER
Lack of Assocation of Glutathione S-transferase T1 Gene Null and Susceptibility to Lung Cancer in China: a Meta-analysis. Asian Pacific Journal of Cancer Prevention, 2013; 14(12): 7215-7219.
)