Standardized Uptake Values Highly Correlate with Tumor Size and Fuhrman Grade in Patients with Clear Cell Renal Cell Carcinoma

Background: We investigated the correlation between standardized uptake value (SUVmax), tumor size andFuhrman grade in patients with renal cell carcinoma (RC). Materials and
Methods: We retrospectively analyzedthe data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) betweenJanuary 2005 and March 2014.
Results: Avarage tumor sizes were 5.64±1.85, 6.85±2.24 and 7.98±2.45 in low,medium and high SUVmax groups, respectively. The Spearman’s correlation coefficient between the tumor sizeand SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001).
Conclusions:SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologicallyconfirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.