Comparative Study of Contrast-Enhanced Ultrasound Qualitative and Quantitative Analysis for Identifying Benign and Malignant Breast Tumor Lumps


Background: To compare the value of contrast-enhanced ultrasound (CEUS) qualitative and quantitativeanalysis in the identification of breast tumor lumps. Materials and
Methods: Qualitative and quantitativeindicators of CEUS for 73 cases of breast tumor lumps were retrospectively analyzed by univariate andmultivariate approaches. Logistic regression was applied and ROC curves were drawn for evaluation andcomparison.
Results: The CEUS qualitative indicator-generated regression equation contained three indicators,namely enhanced homogeneity, diameter line expansion and peak intensity grading, which demonstratedprediction accuracy for benign and malignant breast tumor lumps of 91.8%; the quantitative indicator-generatedregression equation only contained one indicator, namely the relative peak intensity, and its prediction accuracywas 61.5%. The corresponding areas under the ROC curve for qualitative and quantitative analyses were 91.3%and 75.7%, respectively, which exhibited a statistically significant difference by the Z test (P<0.05).
Conclusions:The ability of CEUS qualitative analysis to identify breast tumor lumps is better than with quantitative analysis.