Background: Oral cancer is in increasing in incidence in Yemen and indeed worldwide. Knowledge regardingrisk factors and early signs in the general population can help in prevention and early detection of the disease.Purpose: The aim of this study was to assess the level of awareness and knowledge of oral cancer in the generalpopulation in Yemen. Materials and Methods: A cross-sectional survey using a self-administered questionnairewas conducted on Yemeni adults aged ≥15 years old. A total of 543 persons participated, the collected databeing analyzed using SPSS software. The significance level was set at p<0.05. Results: Two thirds (71.5%) of theparticipants had heard about oral cancer. Smoking and smokeless tobacco usage were identified as the major riskfactors by 71.5% and 73.7% of the participants, respectively. Only 24.1% and 21.4%, respectively, were able tocorrectly identify red and white lesions as early signs of oral cancer. Knowledge of oral cancer was significantlyassociated with age (p<0.01), gender (p<0.05) and education level (p<0.001). Conclusions: The findings suggestthat the knowledge regarding oral cancer in this population is low. Therefore, educational programs are highlyneeded to improve such knowledge.
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