Radioactive Seed Implantation and Lobaplatin Chemotherapy Are Safe and Effective in Treating Patients with Advanced Lung Cancer

Objecive: To investigate the clinical safety and efficacy of CT-guided 125iodine (125I) seed implantationcombined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol intreating patients with advanced lung cancer. Materials and
Methods: Patients with advanced lung cancer andtreated with spiral CT-guided 125I seed implantation combined with percutaneous intra-tumor injection ofchemotherapy emulsion of lobaplatin and lipiodol were recruited.
Results: Of the 36 patients, there were 40nidi in total. The contrast-enhanced CT evaluation was conducted 60 d after treatment. Response evaluationsuggested that 4 patients achieved complete remission (CR), 24 partial remission (PR), 4 stable disease (SD)and 4 progression disease (PD), with a total response rate of 77.8% (28/36).
Conclusions: CT-guided 125I seedimplantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin andlipiodol are safe and effective in treating patients with advanced lung cancer.