Risk Factors for Thyroid Cancer in Females Using a Logit Model in Lahore, Pakistan


Background: Thyroid cancer (TC) is a more common endocrine malignancy in females and is a major causeof death in developing countries. Therefore the aim of this study was to explore possible risk factors of thyroidcancer in females of Pakistan. Materials and
Methods: This study covered 232 females, including 127 (54.7%)cases and 105 (45.2%) controls, from the INMOL Hospital and Sheikh Zayed Hospital, Lahore. Different riskfactors were explored by the descriptive and inferentially statistics. Odds ratios and 95% confidence intervalsfor different risk factors were computed using logistic regression.
Results: The results showed six risk factors,marital status, family history of thyroid cancer, iodine in the diet, oxidative stress, fast food and fried food, todemonstrate positive significant links to thyroid cancer (odds ratios and 95% confidence intervals of :2.152,1.104-4.198; 2.630, 1.416-4.887; 2.391, 1.282-4.458; 4.115, 2.185-7.750; 3.656, 1.851-7.223; 2.357, 1.268-4.382; and2.360, 1.199-4.643, respectively).
Conclusions: The Oxidative stress, marital status, family history of cancer, fastfood, use of iodine diet and fried food are the risk factors of thyroid cancer in females.