Impact of Omega-3 Fatty Acid Supplements on Gastrointestinal Cancer Patients after Surgery: Beneficial or Useless?


Omega-3 polyunsaturated fatty acids (w-3 PUFAs) are essential nutrients for human beings and theirpotential roles against cancer development and progression have become of wide concern recently. Some studieshave suggested that perioperative supplementation with omega-3 fatty acids may have beneficial effects ingastrointestinal cancer patients undergoing surgery, while other researchers reported contrary results. Thispaper reviews recent research to establish therapeutic effects as well as possible underlying mechanisms of w-3PUFA actions, and to help explain possible reasons for inconsistent results from different institutions.