Background and objective: Today, the chemical materials available in hair dyes are considered risk factors for many cancers, particularly oral cancer. This study was performed to study the effect of occupational exposure on micronucleus (MN) frequency of buccal mucosa cells in hairdressers. Materials and methods: This historical cohort study was performed on 28 hairdressers and 28 control samples. To eliminate the gender variable, all the samples were women and they were matched by age. Buccal mucosa cells were removed using a wet spatula and after fixation, Papanicolaou staining method was applied. The percentage of the cells containing MN was registered. T-test was used to compare the results between the two groups. Results: The mean percentages of MN in buccal mucosa cells of hairdresser’s and control sample were 16.61±4.95 and 8.84±4.74, respectively, with a significant difference (P<0.001). In addition, higher MN mean percentage was reported in subjects working more than 60 hours weekly compared with those working 60 hours and less; however, the difference was not statistically significant (P=0.14). Conclusion: In the present study, hairdressers demonstrate significantly higher average of MN in buccal mucosa cells. Also, it seems increment in their working time can increase MN frequency in these studied samples.
Farhadi, S., Jolehar, M., & Safapour, F. (2018). Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure. Asian Pacific Journal of Cancer Prevention, 19(8), 2131-2134. doi: 10.22034/APJCP.2018.19.8.2131
MLA
Sareh Farhadi; Maryam Jolehar; Fatemeh Safapour. "Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure". Asian Pacific Journal of Cancer Prevention, 19, 8, 2018, 2131-2134. doi: 10.22034/APJCP.2018.19.8.2131
HARVARD
Farhadi, S., Jolehar, M., Safapour, F. (2018). 'Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure', Asian Pacific Journal of Cancer Prevention, 19(8), pp. 2131-2134. doi: 10.22034/APJCP.2018.19.8.2131
VANCOUVER
Farhadi, S., Jolehar, M., Safapour, F. Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure. Asian Pacific Journal of Cancer Prevention, 2018; 19(8): 2131-2134. doi: 10.22034/APJCP.2018.19.8.2131
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