Objective: In the study our aim was to evaluate the cytotoxic activity of different solvent extracts of Annona squamosa seeds. Methods and materials: The four extracts used were petroleum ether, chloroform, ethyl acetate and methanol were tested using cytotoxicity assays. Results: Among the four extracts tested petroleum ether showed maximum cytotoxicity against a panel of cancer cell lines such as nasopharyngeal cancer (KB) cells, lung cancer (A-549) cells, breast cancer (MCF- 7) cells, leukemic (K-562) cells and inhibited the growth of murine cancer cells such as Dalton’s lymphoma ascites (DLA) and Ehrlich ascites carcinoma (EAC). Conclusion: Petroleum ether extract of Annona squamosa seeds showed cytotoxicity towards a panel of cancer cells meanwhile non-significant cytotoxicity towards normal cells.
Vikas, B. , Anil, S. and Remani, P. (2019). Cytotoxicity Profiling of Annona Squamosa in Cancer Cell Lines. Asian Pacific Journal of Cancer Prevention, 20(9), 2831-2840. doi: 10.31557/APJCP.2019.20.9.2831
MLA
Vikas, B. , , Anil, S. , and Remani, P. . "Cytotoxicity Profiling of Annona Squamosa in Cancer Cell Lines", Asian Pacific Journal of Cancer Prevention, 20, 9, 2019, 2831-2840. doi: 10.31557/APJCP.2019.20.9.2831
HARVARD
Vikas, B., Anil, S., Remani, P. (2019). 'Cytotoxicity Profiling of Annona Squamosa in Cancer Cell Lines', Asian Pacific Journal of Cancer Prevention, 20(9), pp. 2831-2840. doi: 10.31557/APJCP.2019.20.9.2831
CHICAGO
B. Vikas , S. Anil and P. Remani, "Cytotoxicity Profiling of Annona Squamosa in Cancer Cell Lines," Asian Pacific Journal of Cancer Prevention, 20 9 (2019): 2831-2840, doi: 10.31557/APJCP.2019.20.9.2831
VANCOUVER
Vikas, B., Anil, S., Remani, P. Cytotoxicity Profiling of Annona Squamosa in Cancer Cell Lines. Asian Pacific Journal of Cancer Prevention, 2019; 20(9): 2831-2840. doi: 10.31557/APJCP.2019.20.9.2831
)