Background: The largest radiological accident to occur in any urban area happened in Goiânia, Brazil, in 1987. One major concern regarding deleterious effects in the population was a possible increase in the breast cancer incidence. This study analyzed trends in the incidence of breast cancer over the 25-year period following the radiological accident. Methods: This ecological, population-based study was conducted to determine the incidence of breast cancer in female residents of Goiânia, Goiás, Brazil, between 1988 and 2012. The data were collected from the Goiânia population-based cancer registry. Crude and age-standardized incidence rates were calculated. The Joinpoint software program was used to calculate annual percent changes (APC) in the incidence of breast cancer. Results: Overall, 7,365 new cases of breast cancer were identified, with an annual crude incidence rate of 23.09/100,000 women in 1988 and of 71.65/100,000 women in 2012. The age-standardized incidence rate was 35.63/100,000 women in 1988 and 65.63/100,000 women in 2012. Analysis of the APC showed a significant annual increase of 4.8% in the incidence between 1988 and 2005 (p<0.0001) followed by stabilization in 2005-2012, with an APC of -3.5% (p=0.1). Conclusion: There was an increase in the incidence of breast cancer in the female residents of Goiânia, Goiás in the first 17 years of evaluation (1988-2004) followed by a period of stabilization until 2012. However, the trends in the incidence suggest a lack of association with the radiological accident.
Rahal, R. M. S., Rocha, M. E., Freitas-Junior, R., Correa, R. D. S., Rodrigues, D., Martins, E., Soares, L. R., & Oliveira, J. C. (2019). Trends in the Incidence of Breast Cancer Following the Radiological Accident in Goiânia: A 25-Year Analysis. Asian Pacific Journal of Cancer Prevention, 20(12), 3811-3816. doi: 10.31557/APJCP.2019.20.12.3811
MLA
Rosemar Macedo Sousa Rahal; Marina Elias Rocha; Ruffo Freitas-Junior; Rosangela da Silveira Correa; Danielle Rodrigues; Edesio Martins; Leonardo Ribeiro Soares; Jose Carlos Oliveira. "Trends in the Incidence of Breast Cancer Following the Radiological Accident in Goiânia: A 25-Year Analysis". Asian Pacific Journal of Cancer Prevention, 20, 12, 2019, 3811-3816. doi: 10.31557/APJCP.2019.20.12.3811
HARVARD
Rahal, R. M. S., Rocha, M. E., Freitas-Junior, R., Correa, R. D. S., Rodrigues, D., Martins, E., Soares, L. R., Oliveira, J. C. (2019). 'Trends in the Incidence of Breast Cancer Following the Radiological Accident in Goiânia: A 25-Year Analysis', Asian Pacific Journal of Cancer Prevention, 20(12), pp. 3811-3816. doi: 10.31557/APJCP.2019.20.12.3811
VANCOUVER
Rahal, R. M. S., Rocha, M. E., Freitas-Junior, R., Correa, R. D. S., Rodrigues, D., Martins, E., Soares, L. R., Oliveira, J. C. Trends in the Incidence of Breast Cancer Following the Radiological Accident in Goiânia: A 25-Year Analysis. Asian Pacific Journal of Cancer Prevention, 2019; 20(12): 3811-3816. doi: 10.31557/APJCP.2019.20.12.3811
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