OVCCA Web Application as Supplementary Material to Facilitate Health Literacy Regarding Carcinogenic Human Liver Fluke: A Randomized Controlled Trial in Thailand

Document Type : Research Articles


1 Division of General Communicable Diseases, Department of Disease Control, Ministry of Public, Health, Nonthaburi, Thailand.

2 Department of Public Health, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.

3 Parasitic Disease Research Center, Suranaree University of Technology, Nakhon Ratchasima, Thailand.

4 Faculty of Public Health, Valaya Alongkorn Rajabhat University, Thailand.

5 Department of Health, Ministry of Public Health, Khon Kaen, Thailand.


Background: Liver fluke, Opisthorchis viverrini, is associated to cholangiocarcinoma which is found frequently in some areas of Southeast Asian countries particularly in Thailand, Lao People Republic Democratic, Cambodia.  This study sought to investigate the effects of an O. viverrini and cholangiocarcinoma (OVCCA) web application to facilitate health literacy regarding O. viverrini in Northeast Thailand. Methods: A randomized controlled trial study was performed among an intervention group (n=63) and a control group (n=63) during a one-year period from July 2019 to May 2020. The intervention group received the health literacy promotion program of O. viverrini information through the OVCCA web application for 6 weeks. The control group received an activity package from the public health department. The success of the program was evaluated at week 24 after the groups finished the last activity. ANCOVA, t-test and multiple logistic regression were used for data analysis for both groups. Results: The scores for knowledge; ability to access, understand, appraise, and apply information; motivation for protection; and practice of O. viverrini prevention were significantly higher for the intervention group than for the control group. The results indicated that a health literacy promotion program through an OVCCA web application could be advantageous for preventing and controlling O. viverrini infection. Conclusion: This intervention may be used as a potential strategy and guideline for self-care and health promotion in other endemic areas.


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