Document Type : Research Articles
Authors
1
Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, Karnataka, India.
2
Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
3
Department of Zoology, School of Bioscience, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore- 641 043, Tamil Nadu, India.
4
Computational Biology Laboratory, Department of Bioinformatics, Bharathiar University, Coimbatore-641046, Tamil Nadu, India.
5
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore-641046, Tamil Nadu, India.
6
Nehru Arts & Science College (Affiliated to Bharathiar University), Coimbatore, Tamilnadu, India.
7
Bharathiar University, Coimbatore, Tamilnadu, India.
8
School of Engineering, Shanghai Jiao Tong University, Shanghai, 200241, China.
Abstract
Background: Cooking oil fumes (COFs) with smoking habits is a substantial risk that aggravates genetic modifications. The current study was to estimate the biological markers of genetic toxicity counting Micronucleus changes (MN), Chromosome Aberrations (CA) and DNA modifications among COFs exposures and control subjects inherent from South India. Materials and Methods: Present analysis comprised 212 COFs with tobacco users and equivalent number of control subjects. Results: High frequency of CA (Chromatid type: and chromosome type) were identified in group II experimental subjects also high amount of MN and DNA damage frequency were significantly (p < 0.05) in both subjects (experimental smokers and non-smokers). Present analysis was observed absence of consciousness among the COFs exposures about the destructive level of health effects of tobacco habits in working environment. Conclusion: COFs exposed workers with tobacco induce the significant alteration in chromosomal level. Furthermore, a high level of rate of genetic diseases (spontaneous abortion) were identified in the experimental subjects. This finding will be helpful for preventive measures of COFs exposed workers and supportive for further molecular analysis
Keywords
Main Subjects
)