Addition of Gallic Acid Overcomes Resistance to Cisplatin in Ovarian Cancer Cell Lines

Document Type : Research Articles

Authors

• Najwa Al Balushi ¹
• Syed Imran Hassan ²
• Nada Abdullah ¹
• Buthaina Al Dhahli ³
• Shadia Al Bahlani ³
• Ikhlas Ahmed ⁴
• Benjamin K Tsang ⁵
• Sergey Dobretsov ^{6, 7}
• Yahya Tamimi ⁸
• Ikram A Burney ^{1, 9}

¹ Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, PC 123, AlKhoud, Muscat, Oman.

² Department of Chemistry, College of Science, Sultan Qaboos University, P. O. Box 36, PC 123, AlKhoud, Muscat, Oman.

³ Department of Allied Health Sciences, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, PC 123, AlKhoud, Muscat, Oman.

⁴ Department of Pharmacology and Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, PC 123, AlKhoud, Muscat, Oman.

⁵ Departments of Obstetrics & Gynecology, Cellular & Molecular Medicine and the Interdisciplinary School of Health Sciences, and the Centre for Infection, Immunity and Inflammation, University of Ottawa; Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, ON K1N 6N5, Canada.

⁶ Department of Marine Science & Fisheries, College of Agricultural & Marine Sciences, Sultan Qaboos University, P. O. Box 34, PC 123, AlKhoud, Muscat, Oman.

⁷ Centre of Excellence in Marine Biotechnology, Sultan Qaboos University, P. O. Box 34, PC 123, AlKhoud, Muscat, Oman.

⁸ Department of Biochemistry, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, PC 123, AlKhoud, Muscat, Oman.

⁹ Panjwani Center for Molecular Medicine and Drug Research, International Center for chemical and Biological Sciences, Karachi, University, Karachi, Pakistan.

Abstract

Keywords

• Ovarian Cancer
• Gallic acid
• Cisplatin
• Cytotoxicity
• Chemo-resistance

Main Subjects

• Medical Biochemistry