The Metastatic Spread of Breast Cancer Accelerates during Sleep: How the Study Design can Affect the Results

Document Type : Editorials

Authors

1 Department of Clinical Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

3 Department of Radiation Oncology, Iran University of Medical Sciences, Tehran, Iran.

Abstract

Metastasis is the most common event that determines survival in patients with breast cancer. The benefits of appropriate sleep in enhancing cancer patients' prognosis have been demonstrated. Likewise, emerging evidence has noted the positive impacts of regular circadian rhythm on cancer survival. Proper sleep and regular circadian rhythm can help to improve the cancer prognosis by enhancing the immune system. Besides, circadian rhythm disruption can assist cancer progression by promoting systemic inflammation. However, a recent study by Diamantopoulou et al. titled “The Metastatic Spread of Breast Cancer Accelerates during Sleep” demonstrated that sleep can aggravate breast cancer metastasis. This article outlines how the study design can affect this controversy.

Keywords

Asian Pacific Journal of Cancer Prevention
Volume 24, Issue 2
February 2023
Pages 353-355

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History

  • Receive Date: 04 February 2023
  • Revise Date: 26 February 2023
  • Accept Date: 24 February 2023

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