Factors Associated with the Quality of Life among Family Caregivers of Cholangiocarcinoma Survivors in Northeastern Thailand

Document Type : Research Articles


1 Faculty of Nursing, Roi Et Rajabhat University, Roi Et,Thailand.

2 Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.

3 Department of Obstetrics and Gynecology, Ang Thong Hospital, Ang Thong, Thailand.

4 Movement Science and Exercise Research Center-Walailak University (MoveSE-WU), Walailak University, Nakhon Si Thammarat, Thailand.

5 Faculty of Nursing, Udon Thani Rajabhat University, Udon Thani, Thailand.


Background: Cholangiocarcinoma (CCA) is a common and usually lethal liver cancer especially in Southeast Asia. Family caregivers (FCs) and their quality of life (QOL) is important for the care process to operate effectively. However, there are only few research articles about the QOL of CCA FCs. The goal of this study was to assess the QOL and its associated factors among CCA FCs. Material and Methods: This cross-sectional study was undertaken with 231 CCA FCs who were the primary FCs for CCA patients in a tertiary hospital in Northeastern Thailand. The QOL was measured using the Thai version of the World Health Organization’s Quality of Life Questionnaire. Multivariate regression models were developed to investigate the predictors of the QOL, including the demographic characteristics, symptoms, anxiety and depression, and support care need. Results: The CCA caregivers had moderate to high QOL for all of four domains: the mean score was 27.03 (SD=2.81) for physical, 23.13 (SD=2.81) for psychological, 11.32 (SD=1.08) for social relationships, and 28.08 (SD=2.81) for environment. Multivariable analysis shows that, symptoms, support care need, age and education level were significant predictors of FCs’s QOL. Moreover. The QOL was lower in younger FCs (p<0.001). Conclusion: Symptoms, support care needs, age, and education level were associated with QOL among FCs for CCA patients. A holistic strategy that includes caregiver training, psychosocial therapies, and proper support may help these FCs for a better QOL.


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