Community-based Screening of Oral Cancer in Selected Districts of Nepal: A Cross-Sectional Study

Shrestha, Gambhir; Gautam, Dej Kumar; Siwakoti, Bhola; Pradhananga, Kishore Kumar; Mulmi, Rashmi

doi:10.31557/APJCP.2023.24.12.4111

Community-based Screening of Oral Cancer in Selected Districts of Nepal: A Cross-Sectional Study

Document Type : Research Articles

Authors

¹ Department of Community Medicine, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.

² Department of Surgical Oncology, B.P. Koirala Memorial Cancer Hospital, Chitwan, Nepal.

³ Department of Cancer Prevention, Control and Research, B.P. Koirala Memorial Cancer Hospital, Chitwan, Nepal.

⁴ Kathmandu Cancer Center, Tathali, Bhaktapur, Nepal.

10.31557/APJCP.2023.24.12.4111

Abstract

Objective: Oral cancer screening plays a vital role in the prevention and control of oral cancer. This study aimed to determine the prevalence of oral potentially malignant disorders (OPMDs) in the Nepalese community. Methods: A cross-sectional study was conducted in six purposively selected districts in Nepal from May to December 2019. It utilized a camp-based approach, where a standardized questionnaire was administered through face-to-face interviews. Screening of oral cancer was performed by direct visualization and palpation. The study included adults aged 18 years and above, while those already diagnosed with oral cancer were excluded. Logistic regression was used to find out the association between OPMDs and the related variables. Results: A total of 1930 participants with a mean age of 44.3 years (SD=15.1) underwent oral cancer screening. Among them, 32% were current tobacco users, 2% were ex-users, and 11% were alcohol consumers. OPMDs, including suspected cancer, were identified in 139 (7.2%, 95% CI=6.1-8.4) participants. The most common lesion detected was leukoplakia (4.2%), followed by submucous fibrosis (1.5%), erythroplakia (0.9%), and palatal changes due to reverse smoking (0.1%). Additionally, 10 participants were suspected of having oral cancer. Older age group (AOR=7.00; 95% CI=2.76-17.77), male gender (AOR=2.52; 95% CI=1.58-4.02), tobacco chewers (AOR = 14.30; 95% CI=8.82-23.19), and smokers (AOR=4.67; 95% CI=2.88-7.57)) were identified as predictors of OPMDs. Conclusion: This study revealed a high prevalence of OPMDs in Nepal, highlighting the need for oral cancer screening. The findings emphasize the importance of developing strategies to reduce tobacco use and implementing tobacco cessation intervention programs in Nepal to alleviate the burden of oral cancer.

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